Pyridines and derivatives
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- (1)
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Filtered Search Results
Medchemexpress LLC Phenol, 4-(2-aminoethyl)-2-methoxy | 554-52-9 | MFCD00060621 | ≥97.0% | 167.21 | C9H13NO2 | 500 MG
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3-Methoxytyramine (3-O-methyl dopamine) is an extracellular metabolite of dopamine used in biochemical and neuromodulator research. It is supplied as a solid (yellow to brown) and as a 10 mM solution in DMSO, with supporting analytical and safety documentation for research use.
- Research-grade dopamine metabolite for biochemical studies.
- Available as solid and as a 10 mM solution in DMSO.
- Purity ≥97.0% with certificate of analysis available.
- Pack sizes include 100 mg, 250 mg, 500 mg, 1 g, and 5 g.
- Safety data sheet and datasheet PDFs provided for handling and analysis.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Insulin Human P.pa 2ug
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Insulin is an important hormone in glucose regulation reducing blood glucose concentrations by increasing cellular permeability to simple sugars amino acids and fatty acids Its multiple effects include accelerating glycolysis promoting pentose phosphate cycle and promoting hepatic glycogen synthesis Insulin Protein Human (P pastoris) is the recombinant human-derived Insulin protein expressed by P pastoris with tag free
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Phenylacetylglycine | 500-98-1 | MFCD00021744 | 99.6% | 193.20 g·mol⁻1 | C10H11NO3 | 1 ML
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Phenylacetylglycine is a gut microbial metabolite reported to activate β2-adrenergic receptor (β2AR) and to exhibit cardioprotective activity in ischemia/reperfusion models. Supplied as a ready-to-use solution for research, it is suitable for studies of endogenous metabolism, receptor signaling, and cardiac injury mechanisms.
- 10 mM solution in DMSO, 1 mL vial.
- High purity (≈99.6%) suitable for research use.
- Molecular formula C10H11NO3; molecular weight 193.20 g·mol⁻1.
- Active in β2-adrenergic receptor assays and metabolite studies.
- Convenient for in vitro experiments and signaling studies.
- Store at -20 °C according to supplier guidance.
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Medchemexpress LLC Sortilin/SORT1 Huma 5ug | 5ug
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The Sortilin/SORT1 protein acts as a sorting receptor in the Golgi apparatus and as a clearance receptor on the cell surface It plays a crucial role in protein transport to lysosomes independent of M6PR Sortilin/SORT1 Protein Human (HEK293 His) is the recombinant human-derived Sortilin/SORT1 protein expressed by HEK293 with C-His labeled tag
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Medchemexpress LLC ESI1 | 99.76% | 355.82 | 50 MG
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ESI1 is a small molecule epigenetic silencing inhibitor that triggers the formation of nuclear condensates of key lipid metabolism regulators SREBP1/2. This action concentrates transcriptional co-activators to drive lipid/cholesterol biosynthesis.
- Promotes myelin regeneration in demyelinated animal models.
- Facilitates de novo myelination on regenerating CNS axons.
- Reverses age-related declines in cognitive abilities.
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Apexbio Technology LLC Kaempferide 491-54-3 5mg
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Kaempferide (CAS 491-54-3) is a plant-derived O-methylflavone studied for phytochemical-mediated regulation of estrogen receptor (ER ) It is designed to modulate ER signaling pathways thereby affecting estrogen-related cellular processes Kaempferide exerts its biological activity primarily by inhibiting the proliferation of ER -overexpressing colon carcinoma cells through a ligand-independent mechanism and inducing G0/G1 cell cycle arrest while elevating antioxidant enzyme activities In in vitro studies kaempferide demonstrates inhibitory activity in ER -overexpressing colon carcinoma cell lines such as HCT8 IC50 values have not yet been clearly established Based on these pharmacological properties kaempferide holds research potential in colorectal cancer prevention and ER -associated pathway modulation
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Medchemexpress LLC Compound 134a | 2636840-37-2 | 98.4% | 566.58 g/mol | C29H32F6N4O | 10 MG
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p53 Activator 5 is a small-molecule research compound that binds mutant p53 and restores its DNA-binding and transcriptional activity, displaying anti-tumor effects in preclinical studies. It is intended for use as a high-purity reagent in in vitro and preclinical investigations of p53-mediated apoptosis and related signaling pathways.
- Restores mutant p53 DNA-binding activity.
- Demonstrates anti-tumor activity in preclinical models.
- Acts as a p53 pathway activator, promoting apoptosis.
- Suitable as a solid research reagent for in vitro studies.
- High purity (98.4%) for reliable experimental results.
- Molecular weight 566.58 g/mol; formula C29H32F6N4O.
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Medchemexpress LLC Ac4GalNAz | 653600-56-7 | >99.9% | C16H22N4O10 | 50 MG
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Ac4GalNAz is an alkyl chain-based PROTAC linker designed for synthesizing PROTACs. It functions as a click chemistry reagent, enabling selective degradation of target proteins by leveraging the intracellular ubiquitin-proteasome system.
- Contains an azide group for click chemistry reactions
- Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne groups
- Participates in strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups
- Facilitates PROTAC synthesis
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Medchemexpress LLC DYRKs-IN-1 hydrochloride | 1386980-55-7 | 99.7% | 50 MG
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DYRKs-IN-1 hydrochloride is a highly potent inhibitor of Dual-specificity tyrosine-phosphorylation-regulated kinases (DYRKs). It demonstrates significant inhibitory activity against DYRK1A and DYRK1B, with IC50 values of 5 nM and 8 nM, respectively. This compound also exhibits notable antitumor activity. Specifically, in vitro studies have shown that DYRKs-IN-1 hydrochloride (referred to as compound 30) enhances the cellular potency against the human colon tumor cell line SW 620, with an EC50 of 27 nM. It is recognized as a potent DYRKs inhibitor.
- Potent inhibitor of Dual-specificity tyrosine-phosphorylation-regulated kinases (DYRKs).
- Targets DYRK1A with an IC50 of 5 nM.
- Targets DYRK1B with an IC50 of 8 nM.
- Demonstrates antitumor activity.
- Increases cellular potency against human colon tumor cell line SW 620 with an EC50 of 27 nM.
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Medchemexpress LLC Remibrutinib | 1787294-07-8 | 99.8% | 1 ML
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Remibrutinib is a potent and orally active Bruton tyrosine kinase (BTK) inhibitor with an IC50 value of 1 nM. It inhibits BTK activity with an IC50 value of 0.023 μM in blood. This compound has the potential for Chronic Urticaria (CU) treatment.
- Potent and orally active Bruton tyrosine kinase (BTK) inhibitor
- Inhibits BTK activity with an IC50 value of 1 nM
- Inhibits BTK activity in blood with an IC50 value of 0.023 μM
- Potential for Chronic Urticaria (CU) treatment
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Medchemexpress LLC N-nitrososarcosine | 13256-22-9 | MFCD00152671 | 98.0% | 118.09 g/mol | C3H6N2O3 | 25 MG
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N-nitrososarcosine is the N-nitroso derivative of sarcosine supplied as a research-grade chemical for analytical, toxicology, and nitrosation studies. It is used as a reference standard and for investigating nitrosamine formation and biological effects.
- Provides a reference for analytical method development and validation.
- Applicable to studies of nitrosation chemistry and nitrosamine toxicology.
- Supplied in milligram quantities suitable for laboratory research.
- Molecular formula C3H6N2O3; molecular weight 118.09 g/mol.
- CAS number 13256-22-9.
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Apexbio Technology LLC Liothyronine Sodium 55-06-1 500mg
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Liothyronine Sodium (55-06-1) is a small-molecule agonist targeting nuclear thyroid hormone receptors hTR and hTR It is designed to activate these receptors thereby modulating transcriptional regulation of genes involved in energy metabolism protein synthesis lipid metabolism and thermogenesis Liothyronine Sodium exerts its biological activity primarily through binding and activating hTR and hTR In in vitro studies Liothyronine Sodium demonstrates agonist activity with EC50 values of 2 33 nM for both hTR and hTR Based on these pharmacological properties Liothyronine Sodium holds research potential in investigating thyroid-related metabolic pathways receptor-ligand interactions and molecular mechanisms underlying thyroid hormone regulation and metabolic disorders
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Medchemexpress LLC SCP1-IN-2 | 2764615-56-5 | 98.77% | C19H17F3N2O6S2 | 1 MG
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SCP1-IN-2 (Compound SH T-65) is a potent and selective covalent inhibitor against SCP1. It promotes REST degradation and reduces transcriptional activity. High levels of REST protein drive tumor growth in some glioblastoma cells. SCP1-IN-2 has potential for research into glioblastoma where growth is driven by REST transcription activity.
- Potent and selective covalent inhibitor against SCP1
- Promotes REST degradation
- Reduces transcriptional activity
- Useful for glioblastoma research where growth is driven by REST transcription activity
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Medchemexpress LLC VCAM-1/CD106 Human 5ug
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VCAM-1/CD106 proteins expressed on endothelial cells critically regulate leukocyte adhesion through integrin interactions initiating calcium channel activation and RAC1-mediated transendothelial migration during inflammation VCAM-1/CD106 Protein Human (HEK293 Fc) is the recombinant human-derived VCAM-1/CD106 protein expressed by HEK293 with C-hFc labeled tag
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![eMolecules 15788-16-6 | 5-Benzimidazolecarboxylic acid | Ambeed | MFCD00011555 | 162.148 | C8H6N2O2 | 97.000 | OC(=O)c1ccc2[nH]cnc2c1 | 10g | 490511827](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000488924.jpg-250.jpg)
eMolecules 15788-16-6 | 5-Benzimidazolecarboxylic acid | Ambeed | MFCD00011555 | 162.148 | C8H6N2O2 | 97.000 | OC(=O)c1ccc2[nH]cnc2c1 | 10g | 490511827
5-Benzimidazolecarboxylic acid | Ambeed | 15788-16-6 | MFCD00011555 | 162.148 | C8H6N2O2 | 97.000 | OC(=O)c1ccc2[nH]cnc2c1 | 10g | 490511827
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